tailieunhanh - Prevalence of HBV in patients suffering from various malignant disorder in tertiary cancer care center in Malwa region of Punjab

Hepatitis B virus (HBV) is a DNA virus belonging to the Hepadnaviridae family that infect humans causing a disease infecting liver cells displaying a substantial hepatic tissue tropism, and inducing chronic liver damage and subsequent Hepato carcinogenesis. In Oncology patients receive packed red blood cell suspensions and other blood products regularly and they are in the high-risk group for infections due to these viruses. In addition to Hepatocellular carcinoma several studies have proved the existence of HBV in some extra hepatic organs and tissues, such as the kidneys, skin, lymph nodes, bone marrow, vessel walls, colon, pancreas as well as stomach. Chemotherapy, which is one of the main modality of treatment for cancer not only suppresses the immune system which cause an increment in HBV DNA (viral load) and damage the liver. In clinical practice, the oncologists deal with a large number of patients undergoing anticancer treatments and both patients and clinicians are unaware about patient infection with HBV thus posing a serious threat to health care professionals and society at large and HBV infection in these cancer patients can results in life-threatening events and poor outcome due to early discontinuation of Chemotherapy. | Prevalence of HBV in patients suffering from various malignant disorder in tertiary cancer care center in Malwa region of Punjab