tailieunhanh - B-Cell linear epitope prediction on VP2 partial coat protein predicted model of CPV-2b isolate using bioinformatics
Canine parvovirus is the major cause of haemorrhagic gastroenteritis in canines worldwide. There is a high morbidity and mortality in the young puppies. The currently available CPV vaccine is protecting from all antigenic strains but still there is vaccination failure as the strains are emerging at higher rate. The VP2 coat protein is the major coat protein it contains many B-cell epitopes against which many neutralizing antibodies can form, this structural protein of parvovirus can produce virus-like particles (VLPs) by a self-assembly process in vitro, making VLPs attractive vaccine candidates. | B-Cell linear epitope prediction on VP2 partial coat protein predicted model of CPV-2b isolate using bioinformatics
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