tailieunhanh - Aberrant promoter methylation of YAP gene and its subsequent downregulation in indian breast cancer patients

YAP, a potent oncogene and major downstream effector of the mammalian Hippo tumor suppressor pathway can act as either oncogene or tumor suppressor gene based on the type of tissue involved. Despite various studies, the role and mechanism through which YAP mediates its tumor suppressor or oncogenic effects are not yet fully understood. | Aberrant promoter methylation of YAP gene and its subsequent downregulation in indian breast cancer patients

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