tailieunhanh - Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer

Aberrant JAK/STAT activation has been detected in many types of human cancers. The role of JAK/ STAT activation in cancer has been mostly attributed to direct transcriptional regulation of target genes by phosphorylated STAT (pSTAT), while the unphosphorylated STAT (uSTAT) is believed to be dormant and reside in the cytoplasm. | Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer

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