tailieunhanh - Study of haematological parameters in pre and post-treated dogs with chemotherapy by doxorubicin and vincristine in canine transmissible venereal tumour

The present study was carried out in twenty-four dogs irrespective of age, breed, sex affected with canine transmissible venereal tumour (TVT). Affected dogs were divided equally into three groups viz. vincristine therapy (Group I) with 7 day cycle and doxorubicin therapy consisting two groups . Group II with 14 day cycle and group III with 21 day cycle. Pre treatment blood sample collection was done before administration of drug . Day 0, 7, 14 in Group I, Day 0, 14, 28 in Group II and Day 0, 21, 42 in Group III. Hematological parameters viz. Haemoglobin, Total erythrocytes count (TEC) and Total luecocyte count (TLC) was undertaken for study. Non-significant but declining trend of Hb concentration, leucopenia and reduction in total erythrocytes count was observed post treatment in Doxorobucin and vincristine chemotherapy. | Study of haematological parameters in pre and post-treated dogs with chemotherapy by doxorubicin and vincristine in canine transmissible venereal tumour