tailieunhanh - Summary of new aspect of the thesis: Experimental study on the safety and effectiveness of TD0014 hard pills for the treatment of male sexual dysfunction

Determine acute and subchronic toxicity of TD0014 in experimental animals; evaluate androgenic activity and effects on erectile function of TD0014 in experimental animals; evaluate the effects of TD0014 on sodium valproate-induced reproductive decline in male rats. | Summary of new aspect of the thesis Experimental study on the safety and effectiveness of TD0014 hard pills for the treatment of male sexual dysfunction MINISTRY OF EDUCATION MINISTRY OF HEALTH AND TRAINING HANOI MEDICAL UNIVERSITY MAI PHUONG THANH EXPERIMENTAL STUDY ON THE SAFETY AND EFFECTIVENESS OF TD0014 HARD PILLS FOR THE TREATMENT OF MALE SEXUAL DYSFUNCTION Specialty Pharmacology and Toxicology Code 62720120 SUMMARY OF DOCTORAL THESIS HANOI 2019 The study was completed at HANOI MEDICAL UNIVERSITY Scientific supervisors 1. Assoc. Prof. Pham Thi Van Anh 2. Assoc. Prof. Nguyen Trong Thong Reviewer 1 Reviewer 2 Reviewer 3 The doctoral thesis was publicly defended in front of the University Council at Hanoi Medical University on The thesis can be found at - National Library of Vietnam - The Library of Hanoi Medical University 1 INTRODUCTION Male sexual dysfunction includes disorders of desire erectile dysfunction abnormal ejaculation orgasmic dysfunction and failure of detumescence these conditions may appear alone or in combination with each other. Researching and seeking drugs for the treatment of male sexual dysfunction originating from medicinal herbs are of great interest to physicians. TD0014 is a preparation of herbal medicines which comprises thirty-two medicinal plants and deer velvet. The composition of TD0014 has several medicinal herbs that have been studied and used since ancient times in traditional folk medicine as an aphrodisiac. However no studies have provided reliable shreds of evidence of their effects on reproductive functions or toxicity when combining them in TD0014. Therefore the study titled quot Experimental study on the safety and effectiveness of TD0014 hard pills for the treatment of male sexual dysfunction quot was carried out to 1. Determine acute and subchronic toxicity of TD0014 in experimental animals. 2. Evaluate androgenic activity and effects on erectile function of TD0014 in experimental animals. 3. Evaluate the .