tailieunhanh - Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma

Podoplanin (PDPN), a transmembrane O-glycoprotein, is up-regulated in many tumors and is involved in tumor metastasis and malignant progression. In previous studies, we generated a functional blocking monoclonal antibody (mAb, SZ168) against the extracellular domain of human PDPN. | Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma

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