tailieunhanh - Indolylimidazoles: Synthetic approaches and biological activities

In this paper, we have reviewed biological activities of natural and synthesized indolylimidazoles and their various synthetic methods. | Indolylimidazoles Synthetic approaches and biological activities Current Chemistry Letters 9 2020 31 50 Contents lists available at GrowingScience Current Chemistry Letters homepage Indolylimidazoles Synthetic approaches and biological activities Narendra Nirwana Chandresh Pareeka and V. K. Swamib a Heterocyclic research Lab. Department of Chemistry S. D. Govt. College Beawar India b Department of Chemistry Govt. Lohia PG College Churu India CHRONICLE ABSTRACT Article history Indolylimidazole compounds that contain both indole and imidazole rings have shown various Received June 12 2019 biological and pharmacological activities. These indolylimidazole compounds have been Received in revised form synthesized and extracted from the plants. In this paper we have reviewed biological activities June 30 2019 of natural and synthesized indolylimidazoles and their various synthetic methods. In recent Accepted July 7 2019 time the substituted indolylimidazole derivatives have synthesized and reported in the Available online July 7 2019 presence of different kind of the catalysts such as strong protic acid HNO3@nano SiO2 Zn2 @KSF and acetic acid and Amberlyst A-15. This review paper is divided into two Keywords categories bases on bioactivities of natural and synthesized indolylimidazole derivatives. Imidazole Pharmacological activities Anticancer Amberlyst A-15 Microwave irradiation 2020 by the authors licensee Growing Science Canada. 1. Introduction Indolylimidazole and its derivatives are an important class of heterocycles. From the literature survey it followed that the presence of imidazole ring in natural and synthesized compounds have shown significant biological activities. It has also appeared that indole ring-containing natural and synthesized compounds have also shown vast biological activities. Indolylimidazole compounds that contain both indole and imidazole rings have showed various biological and pharmacological activities such as .

• Sinh học
• Amberlyst A 15
• Various synthetic methods
• Indole and imidazole rings
• Synthetic approaches and biological activities
• Substituted indolylimidazole derivatives