tailieunhanh - A high-throughput method for dereplication and assessment of metabolite distribution in Salvia species using LC-MS/MS

Dereplication of crude plant extracts through liquid chromatography-mass spectrometry is a powerful technique for the discovery of novel natural products. Unfortunately, this technique is often plagued by a low level of confidence in natural product identification. This is mainly due to the lack of extensive chromatographic and mass spectrometric optimizations that result in improper and incomplete MS/MS fragmentation data. This study proposes a solution to this problem by the optimization of chromatographic separation and mass spectrometry parameters. | Nội dung Text A high-throughput method for dereplication and assessment of metabolite distribution in Salvia species using LC-MS MS