tailieunhanh - Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells

Methylated CpG dinucleotides in promoters are associated with the loss of gene expression in recombinant Chinese hamster ovary (CHO) cells during large-scale commercial manufacturing. | Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells

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