tailieunhanh - Gut microbiota in health and diseases – A review

The gut micro flora plays vital role in health status of the host. Human physiology and nutrition are greatly affected by the majority of microbes living in the gut. The most dominant phyla, making up to 90 percent of the total microbial population in humans are Bacteroidetes and Firmicutes followed by Actinobacteria Proteobacteria, Tenericutes, and Verrucomicrobia. The multiplication and establishment of gut microbiome begins at birth, but the alteration in composition of the microbial community depends upon various factors such as the age, gender, genetic composition, geographic location, environmental factors, diet and health status of an individual. Therefore it is of prior importance to study and understand the composition of gut microbiome of different ethnic groups. The gut flora has a major role in maintaining the homeostasis by controlling nutrient metabolism, metabolic pathways, synthesis and excretion of vitamins, preventing colonization by pathogens, maintenance of intestinal epithelial barrier function and development of systematic and mucosal immune response. It has been suggested that decrease in density, diversity and activity of gut microbiota (or dysbiosis) can lead to many diseases such as obesity and metabolic syndrome, cancer promotion, inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn‘s disease (CD), irritable bowel syndrome such as constipation, diarrhoea and bloating. The latest researches has revealed new candidate organisms among healthy gut microbiota that are beneficial to gut health and new strategies and individual based therapeutic treatments for correcting dysbiosis occurring in different disease conditions. | EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 8 Number 08 2019 Journal homepage http Review Article https Gut Microbiota in Health and Diseases - A Review Poonam Jethwani1 and Kiran Grover2 department of Life and Basic Sciences Jaipur National University Jaipur-302017 Rajasthan India department of Food and Nutrition Punjab Agricultural University Ludhiana-141001 Punjab India Corresponding author ABSTRACT Keywords Gut microbiota Dysbiosis Prebiotics Probiotics Faecal microbiota transplant Article Info Accepted 12 July 2019 Available Online 10 August 2019 The gut micro flora plays vital role in health status of the host. Human physiology and nutrition are greatly affected by the majority of microbes living in the gut. The most dominant phyla making up to 90 percent of the total microbial population in humans are Bacteroidetes and Firmicutes followed by Actinobacteria Proteobacteria Tenericutes and Verrucomicrobia. The multiplication and establishment of gut microbiome begins at birth but the alteration in composition of the microbial community depends upon various factors such as the age gender genetic composition geographic location environmental factors diet and health status of an individual. Therefore it is of prior importance to study and understand the composition of gut microbiome of different ethnic groups. The gut flora has a major role in maintaining the homeostasis by controlling nutrient metabolism metabolic pathways synthesis and excretion of vitamins preventing colonization by pathogens maintenance of intestinal epithelial barrier function and development of systematic and mucosal immune response. It has been suggested that decrease in density diversity and activity of gut microbiota or dysbiosis can lead to many diseases such as obesity and metabolic syndrome cancer promotion inflammatory bowel disease IBD encompassing ulcerative colitis

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• Gut microbiota
• Faecal microbiota transplant
• Gut microbiota in health and diseases
• Gut micro flora plays vital role
• Microbes living
• Dietary intervention
• Dietary patterns
• Fluctuations of human gut microbiota
• Heavily influenced by diet
• Gut microbiota if dietary fluctuations
• Microbiota in health and disease
• Paediatric diseases
• Infant behavior
• Manipulating the gut microbiota
• Probiotic interventions
• Functional foods
• Gut microbiota model
• Seven functional foods
• Metabolic pathways
• Metabolomics reveals impact
• BMC Veterinary Research
• Gut morphology
• Local inflammation
• Modulating gut microbiota
• Adequate sophorolipid
• BMC Cancer
• Childhood acute lymphoblastic leukemia
• Microbiota dysbiosis
• Gut microbiota profile
• Ribosomal RNA sequencing
• Pulmonary tuberculosis
• Critical role
• Gut lung axis
• 16SrDNA sequencing analysis
• Young adult
• Psycho oncology
• Dysbiosis induced systemic inflammation
• Breast cancer
• Breast microbiota
• Endocrine disruptors
• Environmental pollutants
• BMC Pediatrics
• Intestinal microbiota
• Allergic diseases
• Microbiota profiling
• Laying hens
• Gut microbiota in laying hens
• Supplementing different levels
• Levels of turmeric powder
• Fed maize soybean meal based diet
• 16S sequencing
• Operational taxonomic units
• Healthy control
• Far infrared
• 16S amplicon sequencing
• Activates GPCRs in mice
• Far infrared radiation induces changes
• Next generation sequencing
• Life health outcomes
• Bifidobacterium abundances
• BMC Bioinformatics
• 16S RNA
• Ecological modelling
• Relative species abundance
• BMC Genomics
• Scylla paramamosain
• Core gut microbiota
• Illumina MiSeq sequencing
• 16S rRNA
• Crohn’s disease
• Escherichia coli
• Gene content
• Inflammatory bowel diseases
• Simulated gastric
• Small intestinal juices
• In vitro fermentation
• Human gut microbiota of polysaccharides
• Cicer arietinum l hulls
• Genome Biology
• Human development
• Microbiota maturation
• Specific metabolic pathways
• Honey bees
• Health biomarkers
• Supplemental nutrition
• Gastrointestinal helminth infection
• High resource usage
• Antimicrobial drugs
• Intramuscular fat content
• Lipid metabolism
• Skeletal muscle
• Tylosin containing diet
• Carbohydrate polymers
• Faecalibacterium genera
• Bacteroidetes ratio
• Klebsiella genus
• Turkish Journal of Biology
• Tạp chí Sinh học
• Parkinson’s disease
• Aerobic exercise training
• 16S rRNA gene sequencing
• Medical sciences
• Microbiota in maintaining homeostasis
• Enteroendocrine cells in maintaining homeostasis
• The human digestive tract
• Microbiota gut brain axis
• Gastrointestinal peptides