tailieunhanh - The economic burden of prematurity in Canada

Preterm birth is a major risk factor for morbidity and mortality among infants worldwide, and imposes considerable burden on health, education and social services, as well as on families and caregivers. | Johnston et al. BMC Pediatrics 2014 14 93 http 1471-2431 14 93 BMC Pediatrics RESEARCH ARTICLE Open Access The economic burden of prematurity in Canada I43ricc i K l Inhncfnn1 k TithQrinQ rEmnr-H2 Ellon I6irrj1 PumcilTi n2 nHonn A orio E o A n1 3 Do nolo Rronli 4 Karissa M Johnston Katherine uoucil Ellen Korol rdllieid Vo uyilcliuwcdc Eyawo rdlllcld DldUt and Adrian Levy1 5 Abstract Background Preterm birth is d major risk factor for morbidity and mortality among infants worldwide and imposes considerable burden on health education and social services as well as on families and caregivers. Morbidity and mortality resulting from preterm birth is highest among early 28 weeks gestational age and moderate 28-32 weeks preterm infants relative to late preterm infants 33-36 weeks . However substantial societal burden is associated with late prematurity due to the larger number of late preterm infants relative to early and moderate preterm infants. Methods The aim in this study was to characterize the burden of premature birth in Canada for early moderate and late premature infants including resource utilization direct medical costs parental out-of-pocket costs education costs and mortality using a validated and published decision model from the UK and adapting it to a Canadian setting based on analysis of administrative population-based data from Québec. Results Two-year survival was estimated at for early preterm infants for moderate preterm infants and for late preterm infants. Per infant resource utilization consistently decreased with age. For moderately preterm infants hospital days ranged from at age two to at age ten. Cost per infant over the first ten years of life was estimated to be 67 467 for early preterm infants 52 796 for moderate preterm infants and 10 010 for late preterm infants. Based on population sizes this corresponds to total national costs of million for early preterm infants million for .