tailieunhanh - Effect of cholesterol and niacin supplementation on serum lipid profile in experimentally induced renal dysfunction in wistar rats

Study was conducted on 84 adult male Wistar rats for duration of sixty days. Animals were divided into twelve equal groups and treatments were applied as 2x3x2 factorial design with 2 renal conditions (Normal and Compromised); 3 cholesterol supplementation levels (0%, and 1% w/w on DM basis) and 2 niacin supplementation levels (Unsupplemented and Supplemented @ 100 mg/kg body weight per day orally). Renal dysfunction was induced in respective groups by daily intra-peritoneal injection of gentamicin @ 80mg/kg body weight for 8 days. Blood samples were collected on 0th, 20th, 40th and 60th day of experiment to study lipid profile. | Effect of cholesterol and niacin supplementation on serum lipid profile in experimentally induced renal dysfunction in wistar rats

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