tailieunhanh - Detection of Aminoglycoside-Acetyl transferase enzyme gene (aac(6')-Ib-cr) among ciprofloxacin resistant isolates from the Sudan
The aim of this study was to determine the prevalence of aac(6')-Ib-cr gene among seventy-two urinary and wound enterobacterial pathogens that were ciprofloxacin-resistant and ESBL producers from the Sudan. All the seventy-two isolates were screened by PCR for the presence of the aac(6')- Ib-cr gene. The new variant of the aminoglycoside acetyle transferase enzyme (aac(6')-Ib-cr) gene was detected among 52 of the 72 test isolates (72%) including Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae and Salmonella spp. This finding shows that the new variant aminoglycoside-acetyl transferase gene conferring resistance to ciprofloxacin is highly prevalent (72%) among the isolates from Sudan. This is the first study to report on the detection of aminoglycoside-acetyl transferase enzyme gene from the Sudan. | Detection of Aminoglycoside-Acetyl transferase enzyme gene (aac(6')-Ib-cr) among ciprofloxacin resistant isolates from the Sudan
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