tailieunhanh - Evaluation of skin expression profiles in cattle of Bos indicus and Bos taurus lineage following Rhipicephalus annulatus infestation and molecular characterisation of S100A8 Gene

In tropical countries, a huge drain in profitability of animal production sector is attributed to tick and tick- borne diseases (TTBD). Traditional tick control measures are riddled by development of acaricide resistance in ticks and possibility of environmental pollution. Identifying and propagating naturally resistant breeds of cattle in endemic regions is a more efficient method in the long run. Marker assisted selection (MAS) which applies genomic information along with conventional selection in cattle breeding is a probable solution. S100A8 encodes a protein with profound pro-inflammatory, antimicrobial and antifungal activities in skin. Differential expression of the gene in the wake of Rhipicephalus annulatus infestation in Vechur a native breed of cattle in comparison to crossbred Holstein Friesian (CBHF) was studied using quantitative polymerase chain reaction (qPCR). The exons and introns of S100A8 gene were characterized in three genetic groups, Vechur, Kasargode (Bos indicus) and crossbred Holstein Friesian (Bos taurus), to identify the single nucleotide polymorphism (SNPs) present in among different populations. | Evaluation of skin expression profiles in cattle of Bos indicus and Bos taurus lineage following Rhipicephalus annulatus infestation and molecular characterisation of S100A8 Gene

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