tailieunhanh - Characterization of CONS isolated from clinical samples of paediatric cases in a tertiary care hospital

Coagulase negative staphylococci (CoNS) were generally considered to be contaminants in the past having little clinical significance. Over the past two decades, these organisms have become recognized as important agents of human disease. S. epidermidis is the predominant agent in nosocomial infection, bacteremia, surgical wound and urinary tract infections. Their pathogenic potential is being increasingly understood and also causing problems to clinicians because of their drug resistance. Characterization of CoNS isolated from clinical samples of paediatric cases, their antibiogram and methicillin resistance. The study was conducted from December 2014 to August 2015. The organisms were identified and speciation was done by standard biochemical reactions. Antibiotic susceptibility testing was done by Kirby-Bauer disk diffusion method and following Clinical laboratory standards institute guidelines (2015). The maximum isolates were from female patients 21 (55%) than male patients 17 (45%). Most common age group affected was Neonate (1-28 days) (29%) in both sex followed by Infant (29 days -12 months) in female (13%) and in male (8%). The majority of CoNS species isolated were S. epidermidis 19 (50%), followed by S. haemolyticus 9 (24%), S. xylosus 3 (8%), S. lugdunensis 2 (5%), S. hominis 2 (5%), S. cohnii 2 (5%) and S. saprophyticus 1(3%). S. epidermidis was the predominant species isolated. The most effective antibiotics were Linezolid and Amikacin. | Characterization of CONS isolated from clinical samples of paediatric cases in a tertiary care hospital