tailieunhanh - Seroprevalance of Parvovirus B19 among kidney transplant in Libya

Parvovirus B19 is a single strand DNA virus belongs to the Parvoviridia family and only parvovirus known to be a pathogen in human. It is causing several problems in human especially in immunosuppressed patients such as organ transplant recipients. In kidney transplant patients parvovirus B19 can continue for years due to failure of the immune response and it may be associated with chronic clinical manifestations such as anemia and another reticuloncytopenia. Fifty renal transplant patient who checked up in two main kidney transplant centers in Libya. During the 2017 in different years post transplantation, the blood samples were collected support by questioner include some information about patient. All samples were analyzed by enzyme-linked immunosorbent assay technique (ELISA) for antibody detection of Parvovirus B19 IgM and parvovirus B19 IgG depended on indirect ELISA principles. The seropositive of Parvovirus B19 rate was 6% for IgM (acute infection) and 66% for IgG (chronic infection). Seropositive of ParvovirusB19 in Libyan kidney transplant (Both IgM, IgG) depends on age; most age affected was between 20-39 years old. The conclusion demonstrated that ParvovirusB19 common among kidney transplant in Libya and 35% of Libyan kidney transplant patients were susceptible to the infection by B19 (do not have antibodies). | Seroprevalance of Parvovirus B19 among kidney transplant in Libya