tailieunhanh - Haemato-biochemical alterations in Tuberculin positive dogs

A total of 368 dogs brought to the Teaching Veterinary Clinical Complex, Guwahati, Assam, India were screened for tuberculosis using tuberculin skin test (TST) technique and out of which a total of 6 dogs each from both the reactor and non-reactor group were included for the study. Hemogram of tuberculin positive reactors revealed significant (P≤) reduction in Hb, PCV, TEC, TLC, neutrophils and MCHC when compared to tuberculin negative reactors. Alterations in biochemical parameters included significant (P≤) increase in serum Aspartate transaminase (AST), Alanine transaminase (ALT) and Alkaline phosphatase (ALP) and serum calcium concentrations and reduced serum albumin and inorganic phosphorous. | 2020 9 3 2997-3001 EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 9 Number 3 2020 Journal homepage http Original Research Article https Haemato-Biochemical Alterations in Tuberculin Positive Dogs Acheenta G. Barua1 Koushik Kakoty2 Uttam Rajkhowa1 Pranjal M. Nath1 and Nur Abdul Kader1 1 Department of Velerinary Public Health College of Velerinary Science Assam Agricultural University Khanapara Guwahati-781022 India 2Department of Veterinary Public Health College of Veterinary Science Assam Agricultural University Joyhing North Lakhimpur- 787051 India Corresponding author ABSTRACT Keywords Blood biochemical dog reactor tuberculosis Article Info Accepted 25 February 2020 Available Online 10 March 2020 A total of 368 dogs brought to the Teaching Veterinary Clinical Complex Guwahati Assam India were screened for tuberculosis using tuberculin skin test TST technique and out of which a total of 6 dogs each from both the reactor and non-reactor group were included for the study. Hemogram of tuberculin positive reactors revealed significant P reduction in Hb PCV TEC TLC neutrophils and MCHC when compared to tuberculin negative reactors. Alterations in biochemical parameters included significant P increase in serum Aspartate transaminase AST Alanine transaminase ALT and Alkaline phosphatase ALP and serum calcium concentrations and reduced serum albumin and inorganic phosphorous. Introduction Among several closely related species causing tuberculosis TB in humans and animals the most important are M. tuberculosis and M. bovis Pesciaroli et al. 2012 . Companion animals mainly dog living in contact with TB patients are at great risk of exposure to this pathogen Snider et al. 1971 . Dogs may also occasionally suffer from tuberculosis caused by M. tuberculosis for which a human considered the only reservoir host Typically canine