tailieunhanh - Risk factors and antibiotic sensitivity pattern of Staphylococcus Aureus isolates from suppurative lesions at a Tertiary Care Hospital

The early detection of Methicillin resistance along with its risk factors is of prime importance in the prognosis of S. aureus infections. The marked difference between the antibiogram of MRSA and MSSA isolates creates a difficult scenario in initiating treatment for S. aureus infections. The study aims to identify the risk factors and antibiotic sensitivity pattern of MRSA from pus samples. The present study was conducted at the Department of Microbiology, Kanyakumari Medical College from September 2015 to August 2016 from 100 non-duplicate S. aureus isolates from pus samples. The S. aureus isolates were confirmed by standard methods and methicillin resistance detected by Cefoxitin (30µg) disc. The antibiotic sensitivity pattern was interpreted as per CLSI guidelines. Among the 34 MRSA isolates, 25 were from males and 9 from females of which majority 9(36%) were from boys of ≤15 years of age. Among the risk factors associated with MRSA, surgery had accounted for and diabetes . Resistance to Erythromycin, Gentamicin and Ciprofloxacin was increasingly noted among MRSA isolates and all of them were sensitive to Vancomycin, Teicoplanin, Tigecycline and Linezolid. The early detection of Methicillin resistance among S. aureus together with timely and ideal antibiotic initiation helped by antibiotic sensitivity testing is the need of the hour, which limits the spread of MRSA infections in hospital setting. The role played by a clinical microbiologist in early detection of MRSA is very critical which helps to avoid multidrug resistance, in an era of very limited antibiotics. | Risk factors and antibiotic sensitivity pattern of Staphylococcus Aureus isolates from suppurative lesions at a Tertiary Care Hospital

• Y khoa - Dược
• Methicillin resistance
• Staphylococcus aureus
• Risk factors
• Antibiotic sensitivity
• Suppurative lesions
• Antimicrobial resistance
• Multidrug resistance
• Methicillin resistant Staphylococcus aureus
• Antibiogram of methicillin resistant Staphylococcus aureus
• Tertiary care rural hospital
• Investigate their sensitivity pattern
• Burn patients
• Resistance pattern
• Changing trends in resistance pattern
• Inducible resistance
• Detection of inducible clindamycin resistance
• Erythromycin in clinical isolates
• Prevalence among methicillin resistant
• Disk diffusion method
• Antibiotic susceptibility testing
• Antibiotic resistance pattern
• Tertiary care hospital
• Methicillin resistant staphylococcus
• Methicillin sensitive staphylococcus aureus
• Inducible clindamycin resistance
• Double disc diffusion method
• Methicillin resistance staphylococcus aureus
• Teaching Hospital
• Epidemiological viewpoint
• Clinical samples were processed
• Teaching hospital located
• Laboratory standards institute
• Macrolidelincosamide streptogramin B
• Prevalence of mupirocin resistance
• Health care workers
• Health care workers in a tertiary care center
• Prevalence of carriage
• Epsilometer test
• Retail meat shops and customers
• Clindamycin resistance
• MRSA and inducible clindamycin resistance
• Biofilm formation of clinically important
• Coagulase negative staphylococci
• CoNS isolated
• Antimicrobial susceptibility
• Antibiotic sensitivity pattern
• Methicillin resistant staphylococcus aureus isolated
• Various clinical specimen
• Tertiary care post graduate teaching institute
• Anterior nares
• High level mupirocin resistance
• Low level mupirocin resistance
• Methicillin resistant
• Bacterial isolates
• Impetigo and their resistance pattern
• Coagulase negative staphylococcus
• Biofilm producers
• Staphylococcus Isolates
• Staphylococcus epidermidis
• Nosocomial infections
• Biofilm production
• Staphylococcus epidermidis in blood samples
• Genome Biology
• Antibiotic resistance
• Drug resistant bacterial pathogens poses
• Horizontally transferred
• BMC Pharmacology and Toxicology
• Surgical site infection
• Drug resistance
• Otitis media
• BMC Veterinary Research
• Polymerase Chain Reaction
• Staphylococcus spp
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• Bacteriological profile
• Pyogenic infection
• Extended spectrum beta lactamase