tailieunhanh - A bacteriological study of neonatal septicaemia

Neonatal sepsis is defined as a bacterial infection of the blood in an infant younger than 4 weeks of age. Blood cultures remain the mainstay of laboratory diagnosis of bloodstream infections (BSIs) in infants. The knowledge of bacteriological profile and its antibiotic sensitivity patterns is of immense help in saving lives of neonates with septicaemia. The study was conducted on neonatal blood samples to identify the common pathogens as well as rare and newer pathogenic species causing neonatal septicaemia along with their antibiotic sensitivity to help formulate guidelines for empiric antibiotic therapy in a developing country. | 2020 9 3 1121-1132 EXCELLENT PUBLISHERS InternationalJournal ofCurrent Microbiology andAppliedSciences ISSN 2319-7706 Volume 9 Number 3 2020 Journal homepage http Original Research Article https A Bacteriological Study of Neonatal Septicaemia Pradnya Naik1 and Vishwanath Sannayya2 1 Department of Microbiology Goa Medical College Bambolim Goa 403202 India 2Health Quest Diagnostics Panjim Goa- 403001 India Corresponding author ABSTRACT Keywords neonatal infection septicaemia blood culture konkan BACTEC VITEC antibiotic resistance Article Info Accepted 05 February 2020 Available Online 10 March 2020 Neonatal sepsis is defined as a bacterial infection of the blood in an infant younger than 4 weeks of age. Blood cultures remain the mainstay of laboratory diagnosis of bloodstream infections BSIs in infants. The knowledge of bacteriological profile and its antibiotic sensitivity patterns is of immense help in saving lives of neonates with septicaemia. The study was conducted on neonatal blood samples to identify the common pathogens as well as rare and newer pathogenic species causing neonatal septicaemia along with their antibiotic sensitivity to help formulate guidelines for empiric antibiotic therapy in a developing country. A retrospective study was carried out on neonatal septicaemia for a period of two years from 2018 to 2019 on total 746 blood samples of neonates from konkan region at a private Microbiology lab in North Goa. Blood samples were processed for identification of pathogens along with antibiotic sensitivity by BACTEC and VITEK automated machines. Out of the 746 blood samples received 77 samples showed growth of pathogenic organisms. 65 isolates were gram negative and 12 were gram positive. Amongstgram negative organisms Klebsiellapneumonia and Pseudomonas species were most commonly isolated and amongst the gram positive were CONS and MRSA .Pandorea .