tailieunhanh - Microbiological profile of cases of community acquired pneumonia and antimicrobial susceptibility testing of the etiological agents with special reference to Streptococcus pneumoniae

Community acquired pneumonia is an infection of pulmonary parenchyma. Despite of advancements in antimicrobial therapy, it stills remains a major threat with significant mortality and morbidity. It accounts for about 13-18% of all nosocomial infections. To identify microbial etiology of cases of Community acquired pneumonia, perform antibiotic susceptibility of the isolates & compare the anti-microbial resistance pattern with special reference to Streptococcus pneumoniae. The study was carried out at SRM Medical College Hospital & Research Centre from February 2012 to February 2013. A total of 619 cases with Community acquired pneumonia were included in the study. Sputum from the clinically proven subjects was collected and processed using standard microbiological techniques. Among the 619 clinical samples, a predominant number (n=224) grew Streptococcus pneumoniae which accounts for 37% of the total isolates followed by Klebsiella pneumoniae (7%, n= 44), Moraxella (4%, n=29), Pseudomonas (4%, n=25), Acinetobacter (2%, n=13), Staphylococcus aureus (2%, n=12) and Non-fermenting Gram negative bacilli (1%, n=6) respectively. 40 % (n=247) of the samples grew normal flora while 3% (n=19) of the samples were considered insignificant since sputum Gram stain findings and culture results were discordant. | Microbiological profile of cases of community acquired pneumonia and antimicrobial susceptibility testing of the etiological agents with special reference to Streptococcus pneumoniae