tailieunhanh - Pim-2 modulates aerobic glycolysis and energy production during the development of colorectal tumors

Tumor cells have higher rates of glucose uptake and aerobic glycolysis to meet energy demands for proliferation and metastasis. The characteristics of increased glucose uptake, accompanied with aerobic glycolysis, has been exploited for the diagnosis of cancers. Although much progress has been made, the mechanisms regulating tumor aerobic glycolysis and energy production are still not fully understood. | Pim-2 modulates aerobic glycolysis and energy production during the development of colorectal tumors