tailieunhanh - Magnetoferritin: A novel magnetic protein cage nanocarrier

Nanotechnology is the rapidly expanding field and nanoparticles are omnipresent. Biological nanoparticles are assembled from molecules or atoms synthesized in a biological system. They include magnetosomes, lipoproteins, viruses, exosomes and ferritins A typical instance of a protein cage possessing this native biological function is ferritin. This engineered ferritin, which has the same architecture as natural H-ferritin, is termed magnetoferritin. The iron storage protein ferritin consists of a spherical polypeptide shell (apoferritin) and accommodates various metal ions. During the last two decades, the manipulation of protein cages for the encapsulation of single inorganic nanoparticles into their core to design novel hybrid bioinspired nanoparticles Such hybrid nanoparticles represent an opportunity for advanced nanotechnology applications in the nanodevices, disease diagnosis and therapy, drug delivery, vaccine development and bioassay. | 2019 8 2 182-186 EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 8 Number 02 2019 Journal homepage http Review Article https Magnetoferritin A Novel Magnetic Protein Cage Nanocarrier Sumedha Bobade K. Vijayarani . Tirumurugaan A. Thangavelu S. Vairamuthu and G. Kalaiselvi Department of Animal Biotechnology Madras Veterinary College TANUVAS Chennai Tamilnadu India Corresponding author ABSTRACT Keywords Appoferritn Ferritin Fenobody Magnetoferritin Nanotechnology Article Info Accepted 04 January 2019 Available Online 10 February 2019 Nanotechnology is the rapidly expanding field and nanoparticles are omnipresent. Biological nanoparticles are assembled from molecules or atoms synthesized in a biological system. They include magnetosomes lipoproteins viruses exosomes and ferritins. A typical instance of a protein cage possessing this native biological function is ferritin. This engineered ferritin which has the same architecture as natural H-ferritin is termed magnetoferritin. The iron storage protein ferritin consists of a spherical polypeptide shell apoferritin and accommodates various metal ions. During the last two decades the manipulation of protein cages for the encapsulation of single inorganic nanoparticles into their core to design novel hybrid bioinspired nanoparticles Such hybrid nanoparticles represent an opportunity for advanced nanotechnology applications in the nanodevices disease diagnosis and therapy drug delivery vaccine development and bioassay. Introduction Nanoparticles are the spearheads of the rapidly expanding field of nanotechnology. Among all classes of biological nanoparticles ferritins an ubiquitous iron storage and transport proteins found in most living organisms eubacteria archea plants and animals except yeast. Ferritin was discovered in 1937 by Laufberger as a novel protein structure for .

• Sinh học
• Fenobody magnetoferritin
• Novel magnetic protein
• Magnetic protein cage nanocarrier
• Spherical polypeptide shell
• Advanced nanotechnology applications
• Advanced Molecular
• Dynamics Simulations
• Numerical Integration
• Techniques Based
• Molecular Dynamics
• Systematic Approach