tailieunhanh - Curcumin may enhance the efficacy of anti-leukemia drugs in myeloid leukemia

Myeloid leukemia may be classified as Acute Myeloid Leukemia (AML) or Chronic Myeloid Leukemia (CML) based on its rate of progression. Administration of drugs is the best modality to treat myeloid leukemia, Imatinib mesylate (IM) and cytarabine (cyt) for CML and AML respectively. However, these drugs show severe adverse effects on patients, thereby limiting their therapeutic efficacy. Hence, a safer intervention needs attention. Phytochemicals possess disease fighting properties and hence may be a solution to the problem. Curcumin, a common Indian spice is known to have anti-cancer properties. Present study aims to elucidate the role of curcumin as a chemo-enhancer in myeloid leukemia (CML and AML). | Curcumin may enhance the efficacy of anti-leukemia drugs in myeloid leukemia