tailieunhanh - Study of biofilm production and antimicrobial susceptibility pattern in clinical isolates of proteus species at a Tertiary Care Hospital

Proteus species are among the commonly implicated pathogens in hospital as well as community acquired infections. They cause nosocomial sinusitis, intra-abdominal abscesses, biliary tract infection, surgical site infection, soft tissue infection and osteomyelitis. They cause significant clinical infections, which are difficult to eradicate especially from hosts with wounds, catheterization, underlying diseases and in immunocompromised states. The therapeutic obstacles during Proteus species treatment can be connected with its ability to form biofilm, antibiotic resistance due to biofilm formation leading to persistence of infections. Hence the study is undertaken to find out the ability of Proteus species isolated from different clinical samples to form biofilm and their antibiotic susceptibility pattern. Total of 150 Proteus species isolates from different clinical samples such as urine, purulent material from wounds or abscesses, ear swabs, sputum, blood or aspirates (of joint fluid, pleural fluid, ascitic fluid and pus) collected from patients suspected of bacterial infection at Victoria Hospital, Vani Vilas Hospital, attached to Bangalore Medical College and Research Institute during the period November 2012- November 2014. | Study of biofilm production and antimicrobial susceptibility pattern in clinical isolates of proteus species at a Tertiary Care Hospital