tailieunhanh - An experimental study on the effect of pyrimethamine-loaded niosomes in the treatment of acute toxoplasmosis

Toxoplasma gondii infection has a worldwide distribution. Pyrimethamine (PYR) is the most effective drug for treatment of toxoplasmosis. Unfortunately, it has low oral bioavailability which requires an increase in the dose that results in increased its side effects. Nanostructures showed promising potential to overcome this problem. This study aimed to evaluate the effect of intraperitoneal injection (IP) of PYR-loaded niosomes compared to PYR in the treatment of acute toxoplasmosis in experimentally infected mice. | An experimental study on the effect of pyrimethamine-loaded niosomes in the treatment of acute toxoplasmosis

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