tailieunhanh - Renal dysfunction in heart failure patients

In clinical practice, renal dysfunction is common and associated with re-hospitalization and reduced survival in patients with heart failure. Objectives: To determine the prevalence, characteristics of renal function in heart failure patients and to investigate the relationship between reduced renal function with the degree of heart failure, left ventricular ejection fraction, serum BNP. | Journal of military pharmaco-medicine no5-2018 RENAL DYSFUNCTION IN HEART FAILURE PAITIENTS Nguyen Duy Toan Le Thi Ngoc Han Tran Duc Hung Nguyen Oanh Oanh SUMMARY Background In clinical practice renal dysfunction is common and associated with re-hospitalization and reduced survival in patients with heart failure. Objectives To determine the prevalence characteristics of renal function in heart failure patients and to investigate the relationship between reduced renal function with the degree of heart failure left ventricular ejection fraction serum BNP. Methods and results In 95 patients with heart failure at Department of Cardiology 103 Military Hospital from 2016 November to 2017 April of the patients had worsening renal function. Mean NYHA functional class was for eGFR 60 higher than for eGFR 60 p . There was a significant correlation between eGFR and left ventricular ejection fraction with r p . There was a reversal correlation between eGFR and serum BNP level with r p . Conclusions The more severe HF was the less eGFR was. Estimated GFR correlated positively with left ventricular ejection fraction and negatively with BNP concentration in patients with HF. Keywords Heart failure Renal dysfunction Estimated glomerular filtration rate eGFR . INTRODUCTION Heart failure HF is a serious condition with high mortality despite all modern treatment. Many factors contribute to the poor outcome in HF. Renal dysfunction occurs in acute and chronic HF is associated with reduced survival 4 5 . Prevalance of renal dysfunction is common related to prognosis treatment of HF. Otherwise HF can have similarly detrimental effects on renal function. This intersection between cardiac and renal insufficiencies the so-called cardio-renal interaction is associated with increased rates of morbidity and mortality in patients 8 9 . Therefore investigation of renal dysfunction is necessary to monitor .

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