tailieunhanh - Neonatal bloodstream infections

Neonates are immune-compromised individuals who are prone to infection. Neonatal sepsis has significant morbidity and mortality. This study is a retrospective study to assess the most important bacteria and the risk factors responsible for bloodstream in infection in Neonatal Intensive Care Unit, Mansoura University Hospital, Egypt. | 2020 9 2 1700-1710 EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 9 Number 2 2020 Journal homepage http Original Research Article https Neonatal Bloodstream Infections Rasha M. EL-Morsi1 Soha M. El-Masry2 and Enas Abdulaziz Hamad3 1 Department of Microbiology and Immunology Faculty of Pharmacy Delta University Egypt 2Department of Pharmaceutics Faculty of Pharmacy Damanhour University Damanhour Egypt 3Department of Microbiology and Immunology Faculty of Medicine Mansoura University Egypt Corresponding author ABSTRACT Keywords Neonatal sepsis Klebsiella species Late-onset sepsis Preterm infants Blood stream infections Article Info Accepted 08 January 2020 Available Online 10 February 2020 Neonates are immune-compromised individuals who are prone to infection. Neonatal sepsis has significant morbidity and mortality. This study is a retrospective study to assess the most important bacteria and the risk factors responsible for bloodstream in infection in Neonatal Intensive Care Unit Mansoura University Hospital Egypt. Gram negative bacteria were responsible for most cases of neonatal blood stream infections with Klebsiella pneumoniae accounting for the majority of cases . late-onset sepsis was more common than early-onset sepsis. The preterm infants represented 63 of the overall studied cases. Comparison between demographic data of cases with neonatal sepsis caused by Klebsiella and those caused by other bacteria revealed that there were no statistical significant differences between the two groups. Introduction Neonatal sepsis is a clinical syndrome characterized bacteremia and systemic signs and symptoms during the first month of life or it can be defined as a disseminated disease with a positive blood culture during the first month of life 1 . Sepsis is considered the most important cause of neonatal mortality and