tailieunhanh - Molecular mechanism of action and safety of 5-(3- chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3- thione – a novel anticonvulsant drug candidat
Previously, it was found that 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (TP-315) effectively protects mice from maximal electroshock-induced seizures. The aim of this study was to determine possible interactions between TP-315 and different molecular targets, . GABAA receptors, voltage-gated sodium channels, and human neuronal α7 and α4β2 nicotinic acetylcholine receptors. | Molecular mechanism of action and safety of 5-(3- chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3- thione – a novel anticonvulsant drug candidat
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