tailieunhanh - Optimization of supercritical fluid extraction and HPLC identification of wedelolactone from Wedelia calendulacea by orthogonal array design

The purpose of this work is to provide a complete study of the influence of operational parameters of the supercritical carbon dioxide assisted extraction (SC CO2E) on yield of wedelolactone from Wedelia calendulacea Less., and to find an optimal combination of factors that maximize the wedelolactone yield. In order to determine the optimal combination of the four factors viz. operating pressure, temperature, modifier concentration and extraction time, a Taguchi experimental design approach was used: four variables (three levels) in L9 orthogonal array. Wedelolactone content was determined using validated HPLC methodology. Optimum extraction conditions were found to be as follows: extraction pressure, 25 MPa; temperature, 40 C; modifier concentration, 10% and extraction time, 90 min. Optimum extraction conditions demonstrated wedelolactone yield of ± mg/100 g W. calendulacea Less. Pressure, temperature and time showed significant (p | Optimization of supercritical fluid extraction and HPLC identification of wedelolactone from Wedelia calendulacea by orthogonal array design

• Vật lý
• Supercritical carbon dioxide extraction
• Wedelia calendulacea
• Taguchi orthogonal array design
• High performance liquid chromatography
• Orthogonal array design
• Turkish Journal of Chemistry
• Tạp chí Hóa học
• Dithizone bidentate complexes
• Carbon dioxide extraction
• Noncovalent interactions
• Electron localization function
• Journal of Chemistry
• Usnea longissima (L ) Ach
• Usnic acid (UA)
• Supercritical extraction
• Response surface methodology (RSM)
• Optimization of scco2
• Response surface methodology
• Materials and methods
• Extraction of rambutan seed oil
• Using response surface methodology
• Prosopis juliflora
• Supercritical fluid extraction
• Antifungal activity
• Food poisoned technique
• Per cent of inhibition
• Optimization of ScSO2 extraction
• Seed of rambutan
• The canned fruit industry
• Supercritical carbon dioxide
• Mathematical models