tailieunhanh - Vasculitic syndromes in hepatitis C virus: A review

Vasculitis is a remarkable presentation of the extrahepatic manifestations of HCV. According to the presence or absence of cryoglobulins it is subdivided into two main types: cryoglobulinemic vasculitis and non cryoglobulinemic vasculitis based on the attribution of vasculitis to serum cryoglobulins as a pathogenic factor. The attribution of cryoglobulinemia to HCV represents a success story in the history of immunology, microbiology, and clinical medicine. HCV can bind to and invade lymphocytes, consequently triggering an immune response through different mechanisms | Journal of Advanced Research 2017 8 99-111 Cairo University Journal of Advanced Research REVIEW Vasculitic syndromes in hepatitis C virus A review CrossMark Gaafar Ragab Mohamed A. Hussein Rheumatology and Clinical Immunology Unit Department of Internal Medicine Cairo University Egypt GRAPHICAL ABSTRACT ARTICLE INFO ABSTRACT Article history Received 1 September 2016 Received in revised form 7 November 2016 Accepted 7 November 2016 Available online 2 December 2016 Vasculitis is a remarkable presentation of the extrahepatic manifestations of HCV. According to the presence or absence of cryoglobulins it is subdivided into two main types cryoglobulinemic vasculitis and non cryoglobulinemic vasculitis based on the attribution of vasculitis to serum cryoglobulins as a pathogenic factor. The attribution of cryoglobulinemia to HCV represents a success story in the history of immunology microbiology and clinical medicine. HCV can bind to and invade lymphocytes consequently triggering an immune response through different Abbreviations ANCA antineutrophil cytoplasmic antibody APS antiphospholipid syndrome CAPS catastrophic antiphospholipid syndrome BAL bronchoalveolar lavage CRP C reactive protein CTD connective tissue disease DAA direct acting antiviral drugs ESR erythrocyte sedimentation rate GIT gastrointestinal tract HSP Henoch-Schonlein Purpura HUS hemolytic uremic syndrome IFN a interferon alpha IHD ischemic heart disease MOH minister of health MRI magnetic resonance imaging NHL non Hodgkin lymphoma PAN polyarteritis nodosa PCR polymerase chain reaction PFT pulmonary function test PN peripheral neuropathy RNA ribonucleic acid TIAs transient ischemic attacks TTP thrombotic thrombocytopenic purpura. Corresponding author. Fax 20 2 37939092. E-mail address gragab@ G. Ragab . Peer review under responsibility of Cairo University. Production and hosting by Elsevier http 2090-1232 2016 Production and hosting by Elsevier .

• Y khoa - Dược
• Hepatitis C virus
• Extrahepatic manifestations vasculitis
• Direct acting anti HCV drugs
• Vasculitis to serum cryoglobulins
• Different mechanisms
• BMC Pediatrics
• Hepatitis B virus
• Hepatitis B surface antibody
• HBV antigen
• BMC Cancer
• Hepatocellular carcinoma
• Hepatitis D virus
• Direct acting antivirals
• Prevalence of hepatitis C Virus
• Infection in a patients attending
• Liver failure
• Sequence heterogeneity in the core
• NS5A region of hepatitis C Virus
• IL 28B polymorphisms in predicting treatment response
• Chronic HCV genotype 4 infected
• Pilot study of occult hepatitis C virus
• Occult hepatitis C virus
• Egyptian blood donors
• HCV RNA from plasma
• Blood donors according to presence of HCV RNA
• Phylogenetic tree
• NS5B based genotyping
• Patients from Damietta governorate
• 50 UTR hepatitis C virus
• Cancer risk
• Chronic hepatitis infection
• Confidence intervals
• Cardiovascular risk
• Hepatitis C virus and cardiovascular
• HCV infection
• Increase cardiovascular risk
• Non Hodgkin lymphoma
• Antiviral treatment
• Non Hodgkin’s lymphomas
• BMC Musculoskeletal Disorders
• Human immunodeficiency virus
• Chronic HCV monoinfection
• Ascertain joint pain
• Hepatitis C virus genotype 4
• Chronic hepatitis
• Promoter methylation
• Disease progression
• Solid tumors
• HBV screening
• Hepatitis C
• Hepatitis C virus infection
• Neurological and psychiatric disorders
• Magnetic resonance spectroscopy
• HIV infection
• Direct acting antiviral agents
• Treating chronic hepatitis C infection
• Occult hepatitis C infection
• Clinical relevance
• Lymphoproliferative disorders
• Interferon lambda 3
• Hepatic steatosis
• Chronic hepatitis cirrhosis
• Transfusion transmitted infections
• Tertiary care hospital
• Report medicine
• traditional medicine
• scientific reports
• immune system
• Antimicrobial
• biosynthesis
• Current level of evidence
• Causal association
• Type 2 diabetes
• Insulin resistance
• New era for management
• Chronic hepatitis C virus
• Antiviral agents
• Direct antiviral agents
• Protease inhibitors
• Polymerase inhibitors
• Occult HCV
• Peripheral blood mononuclear cells
• Direct acting antiviral drugs
• Sofosbuvir and daclatasvir
• miR 122
• miR 134
• miR 424
• miR 629
• Receiver operating characteristic
• Summary thesis’ doctor of medicine
• Research of hepatitis C virus genotypes
• Hepatocellular carcinoma patients
• Evaluating relationship between HCV genotypes
• Characteristics laboratory features
• Blood transfusion
• Seroprevalence of Hepatitis B
• C virus
• Blood donors