tailieunhanh - Effect of exercise on serum vitamin D and tissue vitamin D receptors in experimentally induced type 2 Diabetes Mellitus

This work aimed to study the effect of swimming exercise on serum vitamin D level and tissue vitamin D receptors in experimentally induced type 2 Diabetes Mellitus. Sixty adult male rats were divided into control and diabetic groups. Each was further subdivided into sedentary and exercised subgroups. Diabetes Mellitus was induced by a single intraperitoneal dose of streptozotocin (50 mg/kg) dissolved in cold M citrate buffer (pH ). The exercised subgroups underwent swimming for 60 min, 5 times a week for 4 weeks. Serum glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), lipids, vitamin D and tissue Vitamin D receptors (VDR) were evaluated. Significant increase in serum glucose, insulin, HOMA-IR, cholesterol, triglycerides, and low density lipoprotein (LDL) levels in sedentary diabetic rats was detected. On the other hand, high density lipoprotein (HDL), free fatty acids, serum vitamin D and pancreatic, adipose, and muscular VDR showed a significant decrease in the same group. It is evident that all these parameters were reversed by swimming exercise indicating its beneficial role in type 2 Diabetes. In diabetic groups; serum vitamin D was found to be correlated negatively with serum glucose, insulin, HOMA, cholesterol, triglycerides, and LDL and positively correlated with HDL and tissue VDR. In conclusion, Disturbed vitamin D is associated with metabolic impairments in sedentary diabetic rats. Moderate swimming exercise is beneficial in improving these consequences through modulation of vitamin D status. Future studies could be designed to investigate the effect of the combination of vitamin D intake with exercise in diabetic patients. | Effect of exercise on serum vitamin D and tissue vitamin D receptors in experimentally induced type 2 Diabetes Mellitus

• Y khoa - Dược
• Vitamin D receptor
• Serum vitamin D
• Type 2 Diabetes Mellitus
• Experimentally induced
• Effect of exercise
• BMC Pediatrics
• Exercise induced bronchoconstriction
• Airway hyperresponsiveness
• Exercise challenge test
• Mannitol challenge test
• Wujishi Breathing Exercises
• Wujishi breathing exercise
• Dissemination and characteristic features
• Mechanism and therapeutic effect
• Processes and essentials
• BMC Cancer
• Exercise test
• Oesophageal cancer
• Curative treatments
• Significant morbidity
• Neoadjuvant chemotherapy
• BMC Musculoskeletal Disorders
• Low back pain
• Lumbar muscle
• Resistance based exercise
• Muscle atrophy
• BMC Pulmonary Medicine
• Dietary nitrate
• Exercise performance
• Incremental shuttle walk test
• Randomized control trial
• Plyometric exercise
• Hamstring injuries
• Muscle injury
• Hamstring undergoes
• Metabolic syndrome
• Laser acupuncture
• Post menopause
• Laser acupuncture combined
• Diet exercise intervention
• Coriolus versicolor
• Anti fatigue
• Creatine kinase
• Forelimb grip strength
• Exercise training
• skeletal muscle
• PGC 1α
• Biophysiological functions
• Muscular fiber type switching
• Serum biochemical
• Hot climate
• Climatic conditions of Odisha
• Periodicity of exercise
• Stall housed competition horses
• Adolescent psychiatry
• Mental health
• Physical exercise
• Physical fitness
• Cognitive performance
• Self esteem
• School children
• Pulmonary function test
• Breathing frequency
• Exercise testing
• Ventilatory reserve
• Maximal exercise ventilation
• Chronic low back pain
• Exercise therapy
• Motor control
• Abdominal hollowing
• Primitive reflexes
• Stability exercise
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• báo cáo trên tạp chí Medical Sciences
• báo cáo bệnh thú y
• kiến thức bênh thú y
• nghiên cứu bệnh thú y
• Behavioral health
• Köhler effect
• Relational agent
• Softwaregenerated partner
• Virtual reality
• Hamstring muscle
• Y balance test
• Lumbo pelvic rhythm
• Whole body vibration
• Chronic obstructive pulmonary disease
• Functional performance
• Excessive sputum production
• Patient education
• Physical activity
• Hip osteoarthritis
• Quality of life
• Cost benefit analysis
• Improving activity
• total hip replacement
• Total knee replacement
• Strength training
• Therapeutic exercise
• Patellofemoral pain
• Hip strengthening