tailieunhanh - The role of maternal age in fetal development

Maternal age is an important prognostic factor in the development of a fetus. This study aimed to explore the relationship between fetal development and maternal age for women with a history of recurrent miscarriages. This cross - sectional study was conducted at the National Hospital of Obstetrics and Gynecology in Vietnam, from 1st January 2012 to 1st July 2014. A total of 301 newly pregnant patients who had experienced two or more consecutive miscarriages participated in the study. | ---------------------------------------------JOURNAL OF MEDICAL RESEARCH THE ROLE OF MATERNAL AGE IN FETAL DEVELOPMENT Le Thi Anh Dao Ta Thanh Van Hanoi Medical University Maternal age is an important prognostic factor in the development of a fetus. This study aimed to explore the relationship between fetal development and maternal age for women with a history of recurrent miscarriages. This cross - sectional study was conducted at the National Hospital of Obstetrics and Gynecology in Vietnam from 1st January 2012 to 1st July 2014. A total of 301 newly pregnant patients who had experienced two or more consecutive miscarriages participated in the study. The average age of participants was . Based on our findings the relationship between maternal age and the possibility of a baby being born alive can be described in the following equation Possibility of pregnancy e 3-760017 - 0-912499 x mother s age Here e the correlation coefficient R2 . In the case of mothers under 20 years old the possibility of a baby being born alive was found to be 89 - 87 . For mothers age 20 - 29 the percentage was 86 -72 . For mothers age 36 to 40 years old it was 57 - 47 and it decreased to 45 - 30 for those aged above 40 years old. Thus higher maternal age was associated with lower likelihood of giving birth to a live child. Keywords Recurrent miscarriages Maternal age Fetal development I. INTRODUCTION Maternal age is a major factor influencing fetal conception and development. In a register - based study of 634 272 Danish pregnant women who were hospitalized between 1978 and 1992 miscarriage rates were found to be almost identical among women age 30 - 34 years with recurrent miscarriages and those aged 35 - 39 with recurrent miscarriages with a rate of 38 - 40 but increased to 70 in women aged 40 - 44 1 . This would suggest that the impact of age on miscarriage rates among women with recurrent miscarriages is quite modest until age 40 but beyond age 40 age is the .