tailieunhanh - A review of cervical cancer incidence and HPV infection

This review was carried out to provide information regarding cervical cancer incidence and Human Papilloma Virus (HPV) infection worldwide as well as in Vietnam. Cervical cancer is the second most common cancer in women in less developed regions of the globe. An estimation of 445 000 new cases occurred in women from low - and middle-income countries in 2012, comprising 84% of all new cases of cervical cancer worldwide that year. In 2012, approximately 270 000 women died from cervical cancer; more than 85% of these deaths occurred in low - and middle - income countries. There are more than 100 types of HPV, of which at least 13 are cancer-causing. Cervical cancer is caused by sexually acquired infections from certain types of HPV. Two types of HPV (strains 16 and 18) cause 70% of all cervical cancers and precancerous cervical lesions. | --------------------------------------------JOURNAL OF MEDICAL RESEARCH A REVIEW OF CERVICAL CANCER INCIDENCE AND HPV INFECTION Ngo Van Toan Nguyen Duc Hinh Luu Thi Hong Vu Hong Thang Bui Van Nhon Hanoi Medical University This review was carried out to provide information regarding cervical cancer incidence and Human Papilloma Virus HPV infection worldwide as well as in Vietnam. Cervical cancer is the second most common cancer in women in less developed regions of the globe. An estimation of 445 000 new cases occurred in women from low - and middle-income countries in 2012 comprising 84 of all new cases of cervical cancer worldwide that year. In 2012 approximately 270 000 women died from cervical cancer more than 85 of these deaths occurred in low - and middle - income countries. There are more than 100 types of HPV of which at least 13 are cancer-causing. Cervical cancer is caused by sexually acquired infections from certain types of HPV. Two types of HPV strains 16 and 18 cause 70 of all cervical cancers and precancerous cervical lesions. Keywords Cervical cancer incidence HPV I. INTRODUCTION Cervical cancer occurs in tissues of the cervix the organ connecting the uterus and vagina . It is usually a slow-growing cancer that may not present with symptoms but can be found with regular Pap tests a procedure in which cells are scraped from the cervix and looked at under a microscope . Cervical cancer is almost always caused by human papillomavirus HPV infection. Among more than 100 types of HPV several types can cause cervical cancer. The most common types that lead to cervical cancer are HPV 16 and 18. Over the past 40 years the incidence of cervical cancer has reduced significantly in developed countries due to implementation of cervical cancer screening programs. In developing countries the cervical cancer incidence rate has remained stable or increased. If developing countries do not Corresponding author Ngo Van Toan Hanoi Medical University Email .