tailieunhanh - Optimal analysis of the supply of some cancer drugs preparation by dosage at Choray Hospital

o investigate the list of cancer drugs with the highest rate of dividing dose in preparation of cancer drugs by individualized doses at Choray Hospital in year of 2015; to analyze the optimal supply of some typical cancer drugs in drug preparation. | Journal of military pharmaco-medicine n08-2018 OPTIMAL ANALYSIS OF THE SUPPLY OF SOME CANCER DRUGS PREPARATION BY DOSAGE AT CHORAY HOSPITAL Nguyen Van Tung1; Nguyen Quoc Binh2 Nguyen Truong Son2; Nguyen Thi Thu Thuy3 SUMMARY Objectives: To investigate the list of cancer drugs with the highest rate of dividing dose in preparation of cancer drugs by individualized doses at Choray Hospital in year of 2015; to analyze the optimal supply of some typical cancer drugs in drug preparation. Method: Crosssectional description based on retrospective data of cancer drugs at Choray Hospital in the year of 2015. Data were processed by Microsoft Excel 2010. Results were presented in figures and tables. Results: Top 10 active ingredients with the highest rate of dividing dose in 2015: Cytarabine had the highest rate (), followed by etoposide (76%), epirubicin and cisplatin (61%), doxorubicin (52%). The remaining active ingredients (oxaliplatin, carboplatin, pemetrexed, gemcitabine) had a lower percentage and ranged from 20% to 50%. Oxaliplatin had preparation concentration ranged from 10 to 420 mg in different preparation rates. Most of them had the preparation rate under 1%, preparation concentration of 200 mg had the highest rate (), followed by 150 mg (), 100 mg (), the remaining preparation concentrations were below 10%. Doxorubicin had preparation concentration ranged from 5 to 100 mg, most of which had the preparation rate less than 10%. The concentration of 50 mg had the highest rate (), followed by 70 mg (), 60 mg () and concentrations with very low rate were 5 mg, 17 mg, 18 mg and 45 mg (less than 2%). Conclusion: Optimal analysis of the supply of some drugs showed that 3,842 preparations of oxaliplatin and 653 preparation of doxorubicin were inappropriate. Appropriate distribution for each concentration saves billion VND in oxaliplatin and billion in doxorubicin. * Keywords: Cancer drug preparation; Individual dosage; .

• Y khoa - Dược
• Cancer drug preparation
• Individual dosage
• Dividing dose
• Individualized dosage preparation
• Oncology drugs
• BMC Bioinformatics
• Machine learning
• Drug target prioritization
• Network analysis
• Large scale human genomics
• Trial drugs