tailieunhanh - Recent advances and current challenges in allogeneic stem cell transplantation in patients with acquired severe aplastic anemia

Allogeneic stem cell transplantation(SCT)from a human leukocyte antigen(HLA)- matched sibling donor(MSDSCT)is the preferred first-line treatment option for young patients with severe aplastic anemia(SAA). However, only 25% of patients may find an HLA-MSD. SAA patients, who lack a suitable MSD and fail first-line immunosuppressive therapy, may consider SCT from an unrelated donor(URD-SCT)as a treatment option. | Recent advances and current challenges in allogeneic stem cell transplantation in patients with acquired severe aplastic anemia

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