tailieunhanh - Optical biosensors based on multimode interference and microring resonator structures: A personal perspective

By using the transfer matrix method (TMM) and numerical simulations, the designs of the sensor based on silicon waveguides are optimized and demonstrated in detail. We applied our structure to detect glucose and ethanol concentrations simultaneously. A high sensitivity of 9000 nm/RIU, detection limit of 2x10-4 for glucose sensing and sensitivity of 6000nm/RIU, detection limit of for ethanol sensing are achieved. | VNU Journal of Science: Natural Sciences and Technology, Vol. 34, No. 1 (2018) 118-127 Optical Biosensors Based on Multimode Interference and Microring Resonator Structures: A Personal Perspective Le Trung Thanh* Vietnam National University-International School (VNU-IS), 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam Received 01 January 2018 Revised 30 February 2018; Accepted 20 March 2018 Abstract: We review our recent works on optical biosensors based on microring resonators (MRR) integrated with 4x4 multimode interference (MMI) couplers for multichannel and highly sensitive chemical and biological sensors. Our proposed sensor structures have advantages of compactness, high sensitivity compared with the reported sensing structures. By using the transfer matrix method (TMM) and numerical simulations, the designs of the sensor based on silicon waveguides are optimized and demonstrated in detail. We applied our structure to detect glucose and ethanol concentrations simultaneously. A high sensitivity of 9000 nm/RIU, detection limit of 2x10-4 for glucose sensing and sensitivity of 6000nm/RIU, detection limit of for ethanol sensing are achieved. Keywords: Biological sensors, chemical sensors, optical microring resonators, high sensitivity, multimode interference, transfer matrix method, beam propagation method (BPM), multichannel sensor. 1. Introduction sensors. Integrated optical sensors are very attractive due to their advantages of high sensitivity and ultra-wide bandwidth, low detection limit, compactness and immunity to electromagnetic interference [2, 3]. Optical sensors have been used widely in many applications such as biomedical research, healthcare and environmental monitoring. Typically, detection can be made by the optical absorption of the analytes, optic spectroscopy or the refractive index change [1]. The two former methods can be directly obtained by measuring Current approaches to the real time analysis of chemical and biological sensing .