tailieunhanh - Chemical constituents of Chirita drakei Burtt collected in Ha Long bay, Quang Ninh province, Viet Nam

Two triterpenes, an anthraquinone, two lignans and a phenolic compound were isolated from the n-hexane and ethyl acetate extracts of the aerial part of Chirita drakei Burtt collected in islands, on mountain slopes of Ha Long bay, Quang Ninh province. Their structures have been elucidated by mass, NMR spectroscopy and comparison with published data. There are no report on the chemical constituents of Chirita drakei before our study. | Vietnam Journal of Chemistry, International Edition, 55(2): 202-206, 2017 DOI: Chemical constituents of Chirita drakei Burtt collected in Ha Long bay, Quang Ninh province, Viet Nam Part 1. Compounds isolated from the n-hexane and ethyl acetate extracts Nguyen Thi Hoang Anh1,2*, Nguyen Van Tuan2,3, Tran Duc Quan1, Dao Duc Thien1, Nguyen Thanh Tam1, Giang Thi Kim Lien4, Trinh Thi Thuy1, Tran Van Sung1 1 Institute of Chemistry, Vietnam Academy of Science and Technology 2 Graduate University of Science and Technology, Vietnam Academy of Science and Technology 3 Asean College, Van Lam, Hung Yen, Vietnam 4 University of Da Nang Received 14 March 2017; Accepted for publication 11 April 2017 Abstract Two triterpenes, an anthraquinone, two lignans and a phenolic compound were isolated from the n-hexane and ethyl acetate extracts of the aerial part of Chirita drakei Burtt collected in islands, on mountain slopes of Ha Long bay, Quang Ninh province. Their structures have been elucidated by mass, NMR spectroscopy and comparison with published data. There are no report on the chemical constituents of Chirita drakei before our study. Keywords. Chirita drakei, triterpene, anthraquinone, lignin. 1. INTRODUCTION Ha long bay is one of seven new world’s natural wonders, which contains the full value of geology, geomorphology and biodiversity. A set of different plant species were found here, including mangrove plants or species grow in coastal sand of islands, on mountain slopes, on mountain peaks or in store. Until now, 17 endemic plant species have been detected in Ha long bay, for example Hedyotis lecomtei, Allophylus leviscens, Chirita gemella, etc. [1]. Chirita is the oldest genus of the Gesneriaceae family, distributed in Malaysia, Southeast Asia and south of China. Some Chirita species are used in folk medicine as poultice, hemostasis agents or for treatment of hypertension,. [2]. Until now there are only few studies on chemical and .