tailieunhanh - Bài giảng Đánh giá chứng cứ từ nghiên cứu test chẩn đoán

This lecture includes these contents: Đánh giá chứng cứ từ nghiên cứu test chẩn đoán, roles of a new test, defining the clinical question, series of patients, observer test review bias,. Invite you to consult this lecture. | ĐÁNH GIÁ CHỨNG CỨ TỪ NGHIÊN CỨU TEST CHẨN ĐOÁN CEBM Course April 2013 Matthew Thompson Reader, Dept Primary Care Health Sciences Director, Oxford Centre for Monitoring and Diagnosis Deputy Director, Centre for Evidence Based Medicine 2/3 malpractice claims against GPs in UK 40,000-80,000 US hospital deaths from misdiagnosis per year Diagnosis uses Roles of diagnostic tests in health care Roles of a new test Replacement – new replaces old ., CT colonography for barium enema Triage – new determines need for old ., B-natriuretic peptide for echocardiography Add-on – new combined with old ECG and myocardial perfusion scan Bossuyt et al BMJ 2006;332:1089–92 Evaluating genomic tests from bench to bedside: a practical framework. Lin, Thompson, et al. BMC something in press Table 1: Multiple clinical roles of genetic tests in clinical practice Type Purpose Definition Examples Diagnostic Screening Detection or exclusion of a characteristic or disease in asymptomatic persons Fecal DNA to screen for colorectal cancer, SRY genotype to determine fetal sex in first-trimester Diagnosis Rule in or rule out conditions in symptomatic persons Lynch syndrome testing in patients with colorectal cancer, CFTR testing in patients with suspected cystic fibrosis, Factor V Leiden or prothrombin gene testing in patients with thromboembolic disease Prediction Risk assessment Risk of future disease or morbidity from disease in people without the disease Cardiogenomic | ĐÁNH GIÁ CHỨNG CỨ TỪ NGHIÊN CỨU TEST CHẨN ĐOÁN CEBM Course April 2013 Matthew Thompson Reader, Dept Primary Care Health Sciences Director, Oxford Centre for Monitoring and Diagnosis Deputy Director, Centre for Evidence Based Medicine 2/3 malpractice claims against GPs in UK 40,000-80,000 US hospital deaths from misdiagnosis per year Diagnosis uses Roles of diagnostic tests in health care Roles of a new test Replacement – new replaces old ., CT colonography for barium

• Y khoa - Dược
• Đánh giá chứng cứ từ nghiên cứu test chẩn đoán
• Roles of a new test
• Defining the clinical question
• Series of patients
• Observer test review Bias