tailieunhanh - Theranostic gold nanoshells: From synthesis to imaging and photothermal therapy applications

The GNSs were also bioconjugated with anti-HER2 monoclonal antibody for diagnostic breast cancer cells using dark field microscope technique. These GNS NPs play a role as nanoheaters transforming light to heat. With the present of these GNS NPs at volume density of ×1010 in chicken tissue samples, illuminated by 808 nm laser at the power density of 62 the temperature of tissue sample reachs 110˚ C after 20 minutes illumination. | Communications in Physics, Vol. 24, No. 3S2 (2014), pp. 63-70 DOI: THERANOSTIC GOLD NANOSHELLS: FROM SYNTHESIS TO IMAGING AND PHOTOTHERMAL THERAPY APPLICATIONS NGHIEM THI HA LIEN, VU THI THUY DUONG, VU DUONG, DO QUANG HOA, AND TRAN HONG NHUNG Institute of Physics, Vietnam Academy of Science and Technology E-mail: halien@ Received 20 June 2014 Accepted for publication 20 August 2014 Abstract. Gold nanoshells (GNSs) were grown on monodispersed aminoprotpyltriethoxysilane (APTES) functionalized of silica nanoparticles (NPs) cores with varying sizes ranging from 40-180 nm synthesized by Stober route. Gold shells were deposited onto the surface of silica NPs by tetrakis(hydroxymethyl) phosphonium chloride (THPC) and electroless gold plating method. The coverage of the gold nanoshells on the surfaces of the silica NPs was evaluated using UV-VIS/NIR spectrospcopy and transmission electron microscopy (TEM). The plasmon resonance wavelengths of these gold nanoshells were tunable from visible to near infrared region. The GNSs were also bioconjugated with anti-HER2 monoclonal antibody for diagnostic breast cancer cells using dark field microscope technique. These GNS NPs play a role as nanoheaters transforming light to heat. With the present of these GNS NPs at volume density of × 1010 in chicken tissue samples, illuminated by 808 nm laser at the power density of 62 the temperature of tissue sample reachs 110˚ C after 20 minutes illumination. Keywords: gold nanoshells, silica NPs, SPR, dark field image, photothermal therapy. I. INTRODUCTION Gold nanoshells typically consist of a low dielectric spherical core nanoparticle, such as silica or polystyrene, coated with a thin layer of gold whose thickness ranges from a few nanometers to tens of nanometers. GNS NPs are plasmonic materials with intense absorbing and scattering properties. The surface plasmon resonance (SPR) of GNS NPs can be fine-tuned over the visible

• Vật lý
• Communications in Physics
• Theranostic gold nanoshells
• From synthesis to imaging and photothermal therapy applications
• Dark field image
• Anti HER2 monoclonal antibody
• Challenges in particle physics and 3 3 1 models
• Particle physics and 3 3 1 models
• Particle theory and field theory models
• The early Universe
• Non standard model neutrino
• The 3 3 1 models in current particle physics
• Current particle physics
• The Standard Model
• The electro weak
• The process of e+e − → µ +µ
• The randall sundrum model
• Supersymmetric model and unparticle physics
• Randall Sundrum model
• Supersymmetric and Unparticle physics
• Handbook of mechanical engineering
• mechanical engineering
• mechanical design
• mechanical materials
• alloy materials
• Energy Technology
• Compact device model for nanoparticle organic memory transistor’s characterization
• Nanoparticle organic memory transistor
• Hybrid integrated circuit
• Hybrid NOMFET CMOS neuromorphic computing circuit
• Microdroplet in T junction microfluidic system
• Experiment and simulation
• T junction microfluidic system
• Lateral channel decrease
• Optical bistability in three level eit configurations
• Three level eit configurations
• Effects of atomic coherence
• OB in V type system
• Dynamical codimension 2 brane
• Warped six dimensional space time
• Codimension 2 brane
• Warped 6D bulk space time
• Coherent diffractive imaging using table top high harmonic generation
• Coherent diffractive imaging
• Table top high harmonic generation
• Growth of single crystals of methylammonium lead mixedhalide perovskites
• Growth of single crystals
• Methylammonium lead mixedhalide perovskites
• Organo lead mixed halide perovskites
• Tuning electronic transport properties
• Zigzag graphene nanoribbons
• Stone wales defect
• Negative differential resistance
• Asymmetric and symmetric ZGNRs
• The transmembrane italian mutant
• The temperature replica exchange molecular dynamics
• TmE22K trimer structure
• Kinetics probably yield
• Electrochemical fabrication of hybrid plasmonic dielectric nanomaterials
• Gold diamond clusters
• Hybrid plasmonic dielectric nanomaterials
• hybrid plasmonic dielectric materials
• Electron microscopy and optical characterization
• X ray absorption fine structure
• BCC crystals studied
• High order expanded debye waller factors
• Debye Waller factors
• Temperature dependent cumulants
• Nonlinear optics in waveguide arrays and photonic nanowires
• Nonlinear optics in waveguide arrays
• Diffractive resonant radiation
• The spectral body of the pulse
• Radion production in high energy photon collisions
• Solve the hierarchy problem
• Energy loss function for lead
• Local field effect
• Adiabatic local density approximation
• First principles calculations shows good agreemen
• Perturbative nonlinear optics in the extreme ultraviolet region
• The extreme ultraviolet region
• Different extreme ultraviole
• Multiple cycle pulses
• Thermodynamic hadron quark phase transition
• Chiral nuclear matter to quark gluon plasma
• Quark gluon plasma
• Equilibrium properties near critical points
• Phase transitions and critical phenomena
• Chirality of light in hybrid modes
• Vacuum clad ultrathin optical fibers
• Ultrathin optical fibers
• Superchiral outside the fiber
• An advanced logarithmic phase mask for extending depth
• Field of hybrid optical systems
• Modulation transfer functions
• Hybrid imaging system
• Hyperon W production in pp collisions at energy 8 tev
• Investigate the hadronization process
• The RICH detector
• The nominal value
• Profile of the 12co(3 2) emission line detected
• The debris disc of 49 ceti
• Require relatively violent
• Generate secondary gas
• Synthesis and optical characterization
• Building block plasmonic gold nanostructures
• Random nano islands
• Random Au nano islands
• Electrochemical performance of Na0
• 44Mno2 synthesized
• Hydrothermal method using as a cathode material
• Sodium ion batteries
• Sodium ion battery
• Stable during cycling