tailieunhanh - Steroidal diglycosides from the starfish anthenea sibogae
Two steroidal diglycosides namely anthenoside R (1) and anthenoside S (2) were isolated from the methanol extract of the starfish Anthenea sibogae. Their structures were elucidated by means of 1D, 2D-NMR, HR-MS techniques and comparison of their NMR data with reported values. These compounds (1 and 2) were isolated from starfish Anthenea sibogae for the first time. | Vietnam Journal of Science and Technology 56 (4A) (2018) 121-126 STEROIDAL DIGLYCOSIDES FROM THE STARFISH ANTHENEA SIBOGAE Nguyen Anh Hung1, 4, Dinh Thi Ha2, Pham Quoc Long2, Alla A. Kicha3, Tran Thi Thu Thuy1, 2, * 1 Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Ha Noi, Viet Nam 2 Institute of Natural Products Chemistry, VAST, 18 Hoang Quoc Viet, Ha Noi, Viet Nam 3 Department 3G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Institute of Russian Academy of Sciences, Pr. 100-let Vladivostoku 159, 690022 Vladivostok, Rusian Federation 4 Faculty of Chemistry, Hanoi Pedagogical University 2, Xuan Hoa, Vinh Phuc, Viet Nam * Email: Received: 8 September 2018; Accepted for publication: 12 October 2018 ABSTRACT Two steroidal diglycosides namely anthenoside R (1) and anthenoside S (2) were isolated from the methanol extract of the starfish Anthenea sibogae. Their structures were elucidated by means of 1D, 2D-NMR, HR-MS techniques and comparison of their NMR data with reported values. These compounds (1 and 2) were isolated from starfish Anthenea sibogae for the first time. Keywords: Anthenea sibogae, Oreasteridae, starfish, steroid diglycoside, polyhydroxysteroid. 1. INTRODUCTION Anthenea sibogae is an echinoderm species belonging to the genus Anthenea, family Oreasteridae, order Valvatidae, and class Asteroidea. The genus of Anthenea has more than 20 species, distributed mainly in the Indian Ocean and Pacific Ocean [1]. Scientific studies on the chemical composition and biological activity of the genus Anthenea are very limited. Recently, six new polyhydroxysteroidal glycosides, Anthenosides S1-S6 were isolated and identified from the starfish A. sibogae by our research group [2]. Herein, we report the isolation and structure identification of two steroidal diglycosides, anthenoside R (1) and anthenoside S (2) from the methanol extract of starfish A. .
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