tailieunhanh - Fabrication and characterization of porous hydroxyapatite scaffold and nano silver coated on scaffold for tissue engineering application
The obtained results were compared to those of the conventional sintering process and also revealed that microwave processing was a promising method to fabricate PHS for tissue engineering application. On the other hand, nano-Ag, which was used as antibacterial effect to prevent infections, was successfully coated on the PHS by the electroless deposition process. The results showed that nano-Ag spots were homogeneously dispersed on the PHS. | Journal of Science & Technology 127 (2018) 063-066 Fabrication and Characterization of Porous Hydroxyapatite Scaffold and Nano Silver Coated on Scaffold for Tissue Engineering Application Do Van Quang1,*, Byong-Teak Lee2 1 Hanoi University of Science and Technology, No. 1, Dai Co Viet, Hai Ba Trung, Hanoi, Viet Nam 2 Soonchunhyang University, Cheonan-City, Chungnam 330-090, South Korea Received: February 09, 2017; Accepted: June 25, 2018 Abstract Porous hydroxyapatite scaffold (PHS) was fabricated by replica method, where polyurethane foam was filaments coated with a HAp suspension. A subsequent thermal treatment removed the organic materials, remaining the HAp ceramic in the substratum. And then, microwave processing of the PHS was investigated in a dual frequency microwave sintering furnace. Through the optimization of sintering conditions, such as the sintering temperature and holding time, the microstructure and material properties of the PHS were investigated namely pore sizes, grain size, relative density, and compressive strength. The obtained results were compared to those of the conventional sintering process and also revealed that microwave processing was a promising method to fabricate PHS for tissue engineering application. On the other hand, nano-Ag, which was used as antibacterial effect to prevent infections, was successfully coated on the PHS by the electroless deposition process. The results showed that nano-Ag spots were homogeneously dispersed on the PHS. Keywords: HAp, scaffold, nano-Ag, compressive strength 1. Introduction1 some reports attempted to fabricate HAp scaffold by replica method using conventional sintering process. However, there were critical limitations in applying the scaffold to real system because of their low compressive strength [7]. Scaffolds for bone tissue engineering have become a very attractive research field because the scaffold lies at the key of all the new tissue engineering approaches [1]. Various .
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