tailieunhanh - Antimicrobial effects of verbascum georgicum bentham extract

The methanol extract of Verbascum georgicum Bentham (Scrophulariaceae) was investigated for its in-vitro antimicrobial properties. A total of 143 microorganisms belonging to 56 bacteria and 4 fungi and a yeast species were studied using the diskdiffusion method and microdilution assays. | Turk J Biol 29 (2005) 105-110 © TÜB‹TAK Antimicrobial Effects of Verbascum georgicum Bentham Extract Meryem fiENGÜL2, Hatice Ö⁄ÜTCÜ2, Ahmet ADIGÜZEL1, Fikrettin fiAH‹N1, Ayfle Aydan KARA1, ‹sa KARAMAN1, Medine GÜLLÜCE2 1 Biotechnology Application and Research Center, Atatürk University, 25240, Erzurum - TURKEY 2 Department of Biology, Faculty of Arts and Science, Atatürk University, 25240, Erzurum - TURKEY Received: Abstract: The methanol extract of Verbascum georgicum Bentham (Scrophulariaceae) was investigated for its in-vitro antimicrobial properties. A total of 143 microorganisms belonging to 56 bacteria and 4 fungi and a yeast species were studied using the diskdiffusion method and microdilution assays. The results indicated that the methanol extract of V. geopgicum had an inhibitory effect on the growth of all Candida albicans isolates and 17 strains in 10 different species of bacteria, namely Bacillus amyloliquefaciens, B. subtilis, B. cereus, B. pumilus, B. megaterium, B. lentimorbus, B. licheniformis, Pseudomonas putida, P. syringae and Escherichia coli, at different concentrations ranging from to 300 µg/ml. However, it did not show antifungal activity against the isolates of the 4 fungal species tested. Thus, the results suggest that V. georgicum extract possesses compounds with antimicrobial properties that might be utilized for developing new drugs. Key Words: Verbascum georgicum, Antimicrobial activity, Medicinal plant Verbascum georgicum Bentham Ekstrakt›n›n Antimikrobial Etkileri Özet: Verbascum georgicum Bentham’›n metanol ekstrakt›n›n antimikrobiyal özelli¤i in-vitro ortamda araflt›r›ld›. Bir maya 4 fungus 56 bakteri türüne ait 143 mikroorganizma disk-difüzyon ve mikrodilüsyon yöntemleri kullan›larak test edildi. Verbascum georgicum Bentham’›n metanol ekstrakt›n›n Candida albicans izolatlar›n›n hepsine ve Bacillus amyloliquefaciens, B. subtilis, B. cereus, B. pumilus, B. megaterium, B. lentimorbus, B. licheniformis, .