tailieunhanh - Ebook Pediatric pathology - A course review: Part 2

(BQ) Part 2 book “Pediatric pathology - A course review” has contents: Endocrine system, cardiovascular system, the respiratory tract, salivary glands, gastrointestinal system, liver biliary system and gallbladder, the pancreas, bone marrow, transplant pathology, and other contents. | 21 Mandible and Maxilla Normal anatomy/embryology ●● ●● ●● ●● ●● Close proximity of mandible/maxilla to oral cavity; enclose the odontogenic apparatus Odontogenic structures: Combined ectodermal and mesodermal origin Epithelium; also known as ameloblasts, forms the enamel of tooth Stroma; also known as odontoblasts, forms the dentin of tooth Primitive embryonic tissue from early fetal development forms primary and permanent teeth Odontogenic cysts ●● ●● ●● Epithelium-lined cysts common in jaws Derived from remnants of odontogenic epithelium Lined by hyperplastic to thin squamous or cuboidal epithelium INFLAMMATORY CYSTS Periapical (radicular cyst) ●● Most frequent jaw cyst ●● Apex of tooth root, maxillary molars ●● Aftermath of long-standing dental inflammatory disease Residual cyst ●● Cyst attached to apex of tooth and noted after tooth extraction ●● Lined by stratified squamous epithelium, ulcerated, wall has mixed inflammatory infiltrate, giant cells, cholesterol crystals, and dystrophic calcification ●● Treated with curettage DEVELOPMENTAL CYSTS Dentigerous cyst ●● ●● ●● ●● Originates from crown of unerupted permanent tooth (impacted third molar tooth) Lined by thin layer of non-keratinized stratified squamous epithelium Dense inflammatory infiltrate in collagenous stroma May recur, treated with complete removal Odontogenic keratocyst (OKC) ●● Males, posterior mandible ●● Aggressive cyst ●● Lined by parakeratotic squamous epithelium with corrugated/verrucous surface ●● Prominent basal cell layer ●● High recurrence, treated with complete removal ●● If multiple OKC, evaluate for Gorlin syndrome (nevoid basal cell carcinoma) Gingival cyst of newborn ●● Minute cysts, most newborns, disappear within weeks ●● Stratified squamous epithelium lined inclusion cysts Eruption cyst ●● Gingival swelling above an unerupted primary tooth ●● Cyst shows subacute inflammation, hemorrhage, lined by thin non-keratinized stratified squamous epithelium Lateral periodontal .