tailieunhanh - Biological activities of the essential oil and methanol extract of Achillea biebersteinii afan. (asteraceae)

The present work examined the in vitro antimicrobial and antioxidant activities of the essential oil and methanol extract from Achillea biebersteinii Afan. (Asteraceae). The essential oil exhibited antimicrobial activity against 8 bacteria, 14 fungi and the yeast C. albicans, whereas methanolic extract remained inactive. | Turk J Biol 30 (2006) 65-73 © TÜB‹TAK Biological Activities of the Essential Oil and Methanol Extract of Achillea biebersteinii Afan. (Asteraceae) 1 1 2 3 4 5 Özlem BARIfi , Medine GÜLLÜCE , Fikrettin fiAH‹N , Hakan ÖZER , Hamdullah KILIÇ , Hakan ÖZKAN , 6 7 Münevver SÖKMEN , Tülin ÖZBEK 1 Department of Biology, Faculty of Arts and Science, Atatürk University, 25240 Erzurum - TURKEY 2 Department of Genetic and Bioengineering, Faculty of Engineering and Architecture, Kay›sdagi, Yeditepe University, 34755 ‹stanbul - TURKEY 3 Department of Crop Science, Faculty of Agriculture, Atatürk University, 25240 Erzurum - TURKEY 4 Department of Chemistry, Faculty of Art and Science, Atatürk University, 25240 Erzurum - TURKEY 5 The Ministry of Health of Turkey, Erzurum Regional Hygiene Institute, 25240 Erzurum - TURKEY 6 Department of Chemistry, Faculty of Arts and Science Cumhuriyet University, 58140 Sivas - TURKEY 7 Department of Biology, Institute of Natural and Applied Sciences, Atatürk University, 25240 Erzurum - TURKEY Received: Abstract: The present work examined the in vitro antimicrobial and antioxidant activities of the essential oil and methanol extract from Achillea biebersteinii Afan. (Asteraceae). The essential oil exhibited antimicrobial activity against 8 bacteria, 14 fungi and the yeast C. albicans, whereas methanolic extract remained inactive. The antioxidative capacity of the samples was evaluated by using DPPH (2,2-diphenyl-1-picrylhydrazyl) and β-carotene/linoleic acid assays. In both assays, the extract showed better antioxidative capacity than the oil. The extract reduced the stable free radical DPPH with lower IC50 value ( µg/ml) than the oil (8900 µg/ml). In the β-carotene/linoleic acid assay, the samples were not effectively able to inhibit the linoleic acid oxidation, exhibiting only (the extract) and 16% (the essential oil) inhibitions at 2 mg/ml, far below than that of BHT (). Total .

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