tailieunhanh - Antisalmonella activity of selected medicinal plants

Antisalmonella activity of some important plants in the Ayurvedic system of traditional medicine used in India to treat enteric diseases was screened. The aqueous and methanol extracts of 47 medicinal plants were studied for their antibacterial activity against pathogenic Salmonella typhi, Salmonella paratyphi A, and Salmonella typhimurium. | Turk J Biol 33 (2009) 59-64 © TÜBİTAK doi: Antisalmonella Activity of Selected Medicinal Plants Chand PASHA, Shaik SAYEED, Md. Sadath ALI, Md. Ziaullah KHAN Department of Microbiology, Osmania University, Hyderabad-INDIA Received: Abstract: Antisalmonella activity of some important plants in the Ayurvedic system of traditional medicine used in India to treat enteric diseases was screened. The aqueous and methanol extracts of 47 medicinal plants were studied for their antibacterial activity against pathogenic Salmonella typhi, Salmonella paratyphi A, and Salmonella typhimurium. The in vitro antibacterial activity was performed by agar well diffusion method and the results are expressed as the average diameter of zone of inhibition of bacterial growth around the well. Of the herbal extracts tested, 33 plant extracts were found to have antibacterial activity against at least one of the salmonella strains tested with inhibition zones ranging from 9 to 27 mm. Both extracts of Nyctanthes arbortristis, Garcinia indica, Rubia cordifolia, Azadiracta indica, and Momordica charantia exhibited strong anti-salmonella activity. The aqueous extracts were found to be more active than methanol extracts in the present study. Key Words: Medicinal plants, aqueous, methanol extracts, anti-salmonella activity, enteric fever Seçilmiş Tıbbi Bitkilerin Antisalmonella Aktivitesi Özet: Enterik hastalıkları tedavi etmek için Hindistan’da kullanılan geleneksel ilaçların Ayurveda sistemindeki (Hindistan‘ın alt kıtasında ortaya çıkan antik bir sağlık sistemi) bazı önemli bitkilerinin antisalmonella aktivitesi incelenmiştir. 47 tıbbi bitkinin su ve metanol ekstraktlarının patojen Salmonella typhi, Salmonella paratyphi A ve Salmonella typhimurium bakterilerine karşı antibakteriyal aktiviteleri çalışılmıştır. In vitro antibakteriyel aktivite agar kuyucuk yöntemi ile yapılmış ve sonuçlar kuyucuk çevresinde oluşan bakteriyel inhibisyon zon çaplarının ortalaması .