tailieunhanh - Antibacterial activity of four plant extracts used in palestine in folkloric medicine against methicillin resistant Staphylococcus aureus

Ethanolic and hot water extracts from 4 different plant species used in Palestine in popular medicine for the treatment of several ailments of microbial and non-microbial origin were evaluated for potential antimicrobial activity against methicillinresistant Staphylococcus aureus (MRSA). | Turk J Biol 30 (2006) 195-198 © TÜB‹TAK Antibacterial Activity of Four Plant Extracts Used in Palestine in Folkloric Medicine against Methicillin-Resistant Staphylococcus aureus 1 2 2 2 2 Bassam ABU-SHANAB , Ghaleb ADWAN , Naser JARRAR , Awni ABU-HIJLEH , Kamel ADWAN 1 Faculty of Veterinary Medicine, An-Najah National University, Nablus, PALESTINE 2 Department of Biological Sciences, An-Najah National University, Nablus, PALESTINE Received: Abstract: Ethanolic and hot water extracts from 4 different plant species used in Palestine in popular medicine for the treatment of several ailments of microbial and non-microbial origin were evaluated for potential antimicrobial activity against methicillinresistant Staphylococcus aureus (MRSA). Both water and ethanol extracts of Mentha longifolia, Melissa officinalis and Rosa damascena were effective on MRSA. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the ethanolic extract of M. longifolia and M. officinalis were in the range of to mg/ml and to mg/ml, respectively. The ethanolic extract with the greatest antimicrobial activity was that of R. damascena (MIC to mg/ml and MBC to mg/ml). The combination of ethanolic extracts of the plants studied showed synergistic antibacterial activity against MRSA strains. Key Words: Antibacterial activities, plant extracts, methicillin-resistant Staphylococcus aureus Introduction The use of plant compounds to treat infections is an age-old practice in a large part of the world, especially in developing countries, where there is dependence on traditional medicine for a variety of diseases (1,2). Interest in plants with antimicrobial properties has revived as a result of current problems associated with the use of antibiotics (3,4). Methicillin-resistant Staphylococcus aureus (MRSA) is now common in many areas of the world. The frequencies of infections and outbreaks .