tailieunhanh - Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants
The methanolic crude extracts of 12 traditionally used Indian medicinal plants were screened for their antioxidant and free radical scavenging properties using α-tocopherol and butylated hydroxy toluene (BHT) as standard antioxidants. | Turk J Biol 30 (2006) 177-183 © TÜB‹TAK Antioxidant and Free Radical Scavenging Properties of Twelve Traditionally Used Indian Medicinal Plants Farrukh AQIL, Iqbal AHMAD, Zafar MEHMOOD 1 Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh-202002, INDIA 2 Himalaya Drug Company, Najaf Garh Road, New Delhi-110015, INDIA Received: Abstract: The methanolic crude extracts of 12 traditionally used Indian medicinal plants were screened for their antioxidant and free radical scavenging properties using α-tocopherol and butylated hydroxy toluene (BHT) as standard antioxidants. Antioxidant activity was measured by ferric thiocyanate (FTC) assay and compared with the thiobarbituric acid (TBA) method. Free radical scavenging activity was evaluated using diphenyl picryl hydrazyl (DPPH) radicals. The overall antioxidant activity of Lawsonia inermis was the strongest, followed in descending order by Ocimum sanctum, Cichorium intybus, Piper cubeba, Punica granatum, Allium sativum, Delonix regia, Terminalia chebula, Terminalia bellerica, Mangifera indica, Camellia sinensis, and Trigonella foenum-graecum. Seven plants, namely Terminalia chebula, Mangifera indica, Terminalia bellerica, Punica granatum, Ocimum sanctum, Cichorium intybus, and Camellia sinensis, showed strong free radical scavenging activity with the DPPH method. Phytochemical analysis of plant extracts indicated the presence of major phytocompounds, including phenolics, alkaloids, glycosides, flavonoids, and tannins. The phenolic concentrations in the above plants ranged from to mg/g of dry plant extract. A fair correlation between antioxidant/free radical scavenging activity and phenolic content was observed among 9 plants; however, in 3 plants (Piper cubeba, Lawsonia inermis and Trigonella foenum-graecum), no such relationship was observed. The tested plant extracts showed promising antioxidant and free radical scavenging activity,
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