tailieunhanh - Chapter 124. Sexually Transmitted Infections: Overview and Clinical Approach (Part 16)

For hospitalized patients, the following two parenteral regimens have given nearly identical results in a multicenter randomized trial: 1. Doxycycline (100 mg twice daily, given IV or PO) plus cefotetan ( g IV every 12 h) or cefoxitin ( g IV every 6 h). Administration of these drugs should be continued by the IV route for at least 48 h after the patient's condition improves and then followed with oral doxycycline (100 mg twice daily) to complete 14 days of therapy. 2. Clindamycin (900 mg IV every 8 h) plus gentamicin ( mg/kg IV or IM, followed by mg/kg every 8 h) in patients. | Chapter 124. Sexually Transmitted Infections Overview and Clinical Approach Part 16 For hospitalized patients the following two parenteral regimens have given nearly identical results in a multicenter randomized trial 1. Doxycycline 100 mg twice daily given IV or PO plus cefotetan g IV every 12 h or cefoxitin g IV every 6 h . Administration of these drugs should be continued by the IV route for at least 48 h after the patient s condition improves and then followed with oral doxycycline 100 mg twice daily to complete 14 days of therapy. 2. Clindamycin 900 mg IV every 8 h plus gentamicin mg kg IV or IM followed by mg kg every 8 h in patients with normal renal function. Once-daily dosing of gentamicin with combination of the total daily dose into a single daily dose has not been evaluated in PID but has been efficacious in other serious infections and could be substituted. Treatment with these drugs should be continued for at least 48 h after the patient s condition improves and then followed with oral doxycycline 100 mg twice daily or clindamycin 450 mg four times daily to complete 14 days of therapy. In cases with tuboovarian abscess clindamycin rather than doxycycline for continued therapy provides better coverage for anaerobic infection. Follow-Up Hospitalized patients should show substantial clinical improvement within 3-5 days. Women treated as outpatients should be clinically reevaluated within 72 h. A follow-up telephone survey of women seen in an emergency room and given a prescription for 10 days of oral doxycycline for PID found that 28 never filled the prescription and 41 stopped taking the medication early after an average of days often because of persistent symptoms lack of symptoms or side effects. Women not responding favorably to ambulatory therapy should be hospitalized for parenteral therapy and further diagnostic evaluations including a consideration of laparoscopy. Male sex partners should be evaluated and treated empirically .

• Y học thường thức
• Sexually Transmitted Infections
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• Harrisons Internal Medicine
• ABC of sexually transmitted infections
• Main presentations
• Male patients
• Examination techniques
• Genital ulcer disease
• Pelvic inflammatory disease
• Genital growths
• Genital infestations
• Sexual health services
• The sexual health consultation
• Clinical sampling
• Viral hepatitis
• Systemic manifestations
• Sexual health care
• Reproductive tract infections
• Hepatitis B
• Person sexual contact
• Several of these infections
• Tissue transfer
• Illustrated synopsis
• Sexually transmitted diseases
• Adverse drug reactions
• Autoimmune connective tissue diseases
• Cutaneous response
• Bacterial Infections
• Chlamydia trachomatis
• Men Sex Men
• Heterosexual Men
• Mucosal Immunity
• Clinical Approach
• Public health
• Care seeking behavior
• Global public health issue
• Pelvic inflammatory disease
• Ureaplasma urealyticum
• Human papillomavirus
• Mycoplasma genitalium
• Dermatology for the USMLE
• Melanocytic skin disorders
• Malignant skin disorders
• Selected bacterial infections
• Selected fungal infections