tailieunhanh - Chapter 124. Sexually Transmitted Infections: Overview and Clinical Approach (Part 10)

Bacterial Vaginosis: Treatment The standard dosage of metronidazole for the treatment of bacterial vaginosis is 500 mg PO twice daily for 7 days. The single 2-g oral dose of metronidazole recommended for trichomoniasis produces somewhat lower shortterm cure rates. Intravaginal treatment with 2% clindamycin cream [one full applicator (5 g containing 100 mg of clindamycin phosphate) each night for 7 nights] or with metronidazole gel [one full applicator (5 g containing mg of metronidazole) twice daily for 5 days] is also approved for use in the United States and does not elicit systemic adverse reactions. . | Chapter 124. Sexually Transmitted Infections Overview and Clinical Approach Part 10 Bacterial Vaginosis Treatment The standard dosage of metronidazole for the treatment of bacterial vaginosis is 500 mg PO twice daily for 7 days. The single 2-g oral dose of metronidazole recommended for trichomoniasis produces somewhat lower shortterm cure rates. Intravaginal treatment with 2 clindamycin cream one full applicator 5 g containing 100 mg of clindamycin phosphate each night for 7 nights or with metronidazole gel one full applicator 5 g containing mg of metronidazole twice daily for 5 days is also approved for use in the United States and does not elicit systemic adverse reactions. Oral clindamycin 300 mg bid for 7 days and clindamycin ovules 100 g intravaginally once at bedtime for 3 days have also been approved. Unfortunately long-term recurrence . several months later is distressingly common after either oral or intravaginal treatment. A randomized trial comparing this intravaginal gel containing mg of metronidazole with a suppository containing 500 mg of metronidazole plus nystatin the latter not marketed in the United States showed significantly higher rates of recurrent bacterial vaginosis with the regimen this result suggests that higher metronidazole dosages may be important in topical intravaginal therapy. Treatment of male partners with metronidazole does not prevent recurrence of bacterial vaginosis. A randomized trial of orally ingested lactobacilli found reduced rates of recurrent bacterial vaginosis however this result has not yet been either confirmed or refuted. A randomized multicenter trial in the United States found no benefit of repeated intravaginal inoculation of a vaginal peroxide-producing Lactobacillus species following treatment of bacterial vaginosis with metronidazole. A meta-analysis of 18 studies concluded that bacterial vaginosis during pregnancy substantially increased the risk of preterm delivery and of .

• Y học thường thức
• Sexually Transmitted Infections
• Clinical Approach
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• Harrisons Internal Medicine
• ABC of sexually transmitted infections
• Main presentations
• Male patients
• Examination techniques
• Genital ulcer disease
• Pelvic inflammatory disease
• Genital growths
• Genital infestations
• Sexual health services
• The sexual health consultation
• Clinical sampling
• Viral hepatitis
• Systemic manifestations
• Sexual health care
• Reproductive tract infections
• Hepatitis B
• Person sexual contact
• Several of these infections
• Tissue transfer
• Illustrated synopsis
• Sexually transmitted diseases
• Adverse drug reactions
• Autoimmune connective tissue diseases
• Cutaneous response
• Bacterial Infections
• Chlamydia trachomatis
• Men Sex Men
• Heterosexual Men
• Mucosal Immunity
• Public health
• Care seeking behavior
• Global public health issue
• Pelvic inflammatory disease
• Ureaplasma urealyticum
• Human papillomavirus
• Mycoplasma genitalium
• Dermatology for the USMLE
• Melanocytic skin disorders
• Malignant skin disorders
• Selected bacterial infections
• Selected fungal infections